Apigenin blocks IKKα activation and suppresses prostate cancer progression

IKKα has been implicated as a key regulator of oncogenesis and driver of the metastatic process; therefore is regarded as a promising therapeutic target in anticancer drug development. In spite of the progress made in the development of IKK inhibitors, no potent IKKα inhibitor(s) have been identifie...

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Vydáno v:Oncotarget
Hlavní autoři: Shukla, Sanjeev, Kanwal, Rajnee, Shankar, Eswar, Datt, Manish, Chance, Mark R., Fu, Pingfu, MacLennan, Gregory T., Gupta, Sanjay
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741599/
https://ncbi.nlm.nih.gov/pubmed/26435478
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