Role of class I histone deacetylases in the regulation of maspin expression in prostate cancer

Maspin repression is frequently observed in prostate cancer; however, molecular mechanism(s) causing the loss is not completely understood. Here we demonstrate that inhibition of class I histone deacetylases (HDACs) mediate re-expression of maspin plays an essential role in suppressing proliferation...

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Veröffentlicht in:Mol Carcinog
Hauptverfasser: Shankar, Eswar, Pandey, Mitali, Verma, Shiv, Abbas, Ata, Candamo, Mario, Kanwal, Rajnee, Shukla, Sanjeev, MacLennan, Gregory T, Gupta, Sanjay
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7436196/
https://ncbi.nlm.nih.gov/pubmed/32391971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.23214
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