TP53 and MDM2 single nucleotide polymorphisms influence survival in non-del(5q) myelodysplastic syndromes

P53 is a key regulator of many cellular processes and is negatively regulated by the human homolog of murine double minute-2 (MDM2) E3 ubiquitin ligase. Single nucleotide polymorphisms (SNPs) of either gene alone, and in combination, are linked to cancer susceptibility, disease progression, and ther...

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Vydáno v:Oncotarget
Hlavní autoři: McGraw, Kathy L., Cluzeau, Thomas, Sallman, David A., Basiorka, Ashley A., Irvine, Brittany A., Zhang, Ling, Epling-Burnette, P.K., Rollison, Dana E., Mallo, Mar, Sokol, Lubomir, Solé, Francesc, Maciejewski, Jaroslaw, List, Alan F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741464/
https://ncbi.nlm.nih.gov/pubmed/26416416
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