Impact of TP53 mutation variant allele frequency on phenotype and outcomes in myelodysplastic syndromes

Although next-generation sequencing has allowed for the detection of somatic mutations in myelodysplastic syndromes (MDS), the clinical relevance of variant allele frequency (VAF) for the majority of mutations is unknown. We profiled TP53 and 20 additional genes in our training set of 219 patients w...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Leukemia
Main Authors: Sallman, DA, Komrokji, R, Vaupel, C, Cluzeau, T, Geyer, SM, McGraw, KL, Ali, NH Al, Lancet, J, McGinniss, MJ, Nahas, S, Smith, AE, Kulasekararaj, A, Mufti, G, List, A, Hall, J, Padron, E
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864381/
https://ncbi.nlm.nih.gov/pubmed/26514544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2015.304
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki