The relationship of TP53 R72P polymorphism to disease outcome and TP53 mutation in myelodysplastic syndromes

Nonsynonymous TP53 exon 4 single-nucleotide polymorphism (SNP), R72P, is linked to cancer and mutagen susceptibility. R72P associations with specific cancer risk, particularly hematological malignancies, have been conflicting. Myelodysplastic syndrome (MDS) with chromosome 5q deletion is characteriz...

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發表在:Blood Cancer J
Main Authors: McGraw, K L, Zhang, L M, Rollison, D E, Basiorka, A A, Fulp, W, Rawal, B, Jerez, A, Billingsley, D L, Lin, H-Y, Kurtin, S E, Yoder, S, Zhang, Y, Guinta, K, Mallo, M, Solé, F, Calasanz, M J, Cervera, J, Such, E, González, T, Nevill, T J, Haferlach, T, Smith, A E, Kulasekararaj, A, Mufti, G, Karsan, A, Maciejewski, J P, Sokol, L, Epling-Burnette, P K, Wei, S, List, A F
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2015
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382654/
https://ncbi.nlm.nih.gov/pubmed/25768405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2015.11
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