The relationship of TP53 R72P polymorphism to disease outcome and TP53 mutation in myelodysplastic syndromes

Nonsynonymous TP53 exon 4 single-nucleotide polymorphism (SNP), R72P, is linked to cancer and mutagen susceptibility. R72P associations with specific cancer risk, particularly hematological malignancies, have been conflicting. Myelodysplastic syndrome (MDS) with chromosome 5q deletion is characteriz...

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Veröffentlicht in:Blood Cancer J
Hauptverfasser: McGraw, K L, Zhang, L M, Rollison, D E, Basiorka, A A, Fulp, W, Rawal, B, Jerez, A, Billingsley, D L, Lin, H-Y, Kurtin, S E, Yoder, S, Zhang, Y, Guinta, K, Mallo, M, Solé, F, Calasanz, M J, Cervera, J, Such, E, González, T, Nevill, T J, Haferlach, T, Smith, A E, Kulasekararaj, A, Mufti, G, Karsan, A, Maciejewski, J P, Sokol, L, Epling-Burnette, P K, Wei, S, List, A F
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382654/
https://ncbi.nlm.nih.gov/pubmed/25768405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2015.11
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