Mature adipocytes in bone marrow protect myeloma cells against chemotherapy through autophagy activation

A major problem in patients with multiple myeloma is chemotherapy resistance, which develops in myeloma cells upon interaction with bone marrow stromal cells. However, few studies have determined the role of bone marrow adipocytes, a major component of stromal cells in the bone marrow, in myeloma ch...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Liu, Zhiqiang, Xu, Jingda, He, Jin, Liu, Huan, Lin, Pei, Wan, Xinhai, Navone, Nora M., Tong, Qiang, Kwak, Larry W., Orlowski, Robert Z., Yang, Jing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741456/
https://ncbi.nlm.nih.gov/pubmed/26455377
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