Bone Marrow Stromal Cells Derived MCP-1 Reverses the Inhibitory Effects of Multiple Myeloma Cells on Osteoclastogenesis by Upregulating the RANK Expression

Multiple myeloma (MM) cells are responsible for aberrant osteoclast (OC) activation. However, when cocultured monocytes, but not OC precursors, with MM cells, we made a novel observation that MM cells inhibited receptor activator of nuclear factor κB ligand (RANKL)-induced increase of OC differentia...

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Detalhes bibliográficos
Main Authors: Liu, Zhiqiang, Xu, Jingda, Li, Haiyan, Zheng, Yuhuan, He, Jin, Liu, Huan, Zhong, Yuping, Lu, Yong, Hong, Bangxing, Zhang, Mingjun, Lin, Pei, Du, Juan, Hou, Jian, Qian, Jianfei, Kwak, Larry W., Yi, Qing, Yang, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858321/
https://ncbi.nlm.nih.gov/pubmed/24340030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082453
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