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T- and B-cell functions and epitope expression in nonhuman primates immunized with simian immunodeficiency virus antigen by the rectal route.

Transmission of human immunodeficiency virus (HIV) in North America and Europe occurs most commonly through the rectal mucosa during homosexual intercourse. The simian immunodeficiency virus (SIV) macaque model has been used to investigate rectal immunization. The vaccine used was a recombinant SIV...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Lehner, T, Brookes, R, Panagiotidi, C, Tao, L, Klavinskis, L S, Walker, J, Walker, P, Ward, R, Hussain, L, Gearing, J H
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1993
Schlagworte:
Research Article
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47413/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7690967/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.18.8638
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