Inactivated simian immunodeficiency virus vaccine failed to protect rhesus macaques from intravenous or genital mucosal infection but delayed disease in intravenously exposed animals.

Eight rhesus macaques were immunized four times over a period of 8 months with a psoralen-UV-light-inactivated whole simian immunodeficiency virus vaccine adjuvanted with threonyl muramyl dipeptide. Eight unvaccinated control animals received adjuvant alone. Only the vaccinated animals made antibodi...

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Hauptverfasser: Sutjipto, S, Pedersen, N C, Miller, C J, Gardner, M B, Hanson, C V, Gettie, A, Jennings, M, Higgins, J, Marx, P A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1990
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC249390/
https://ncbi.nlm.nih.gov/pubmed/2157886
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