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T- and B-cell functions and epitope expression in nonhuman primates immunized with simian immunodeficiency virus antigen by the rectal route.

Transmission of human immunodeficiency virus (HIV) in North America and Europe occurs most commonly through the rectal mucosa during homosexual intercourse. The simian immunodeficiency virus (SIV) macaque model has been used to investigate rectal immunization. The vaccine used was a recombinant SIV...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Lehner, T, Brookes, R, Panagiotidi, C, Tao, L, Klavinskis, L S, Walker, J, Walker, P, Ward, R, Hussain, L, Gearing, J H
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1993
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47413/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7690967/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.18.8638
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