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T- and B-cell functions and epitope expression in nonhuman primates immunized with simian immunodeficiency virus antigen by the rectal route.

Transmission of human immunodeficiency virus (HIV) in North America and Europe occurs most commonly through the rectal mucosa during homosexual intercourse. The simian immunodeficiency virus (SIV) macaque model has been used to investigate rectal immunization. The vaccine used was a recombinant SIV...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Lehner, T, Brookes, R, Panagiotidi, C, Tao, L, Klavinskis, L S, Walker, J, Walker, P, Ward, R, Hussain, L, Gearing, J H
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47413/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7690967/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.18.8638
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