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Transcription Factors Oct-1 and GATA-3 Cooperatively Regulate Th2 Cytokine Gene Expression via the RHS5 within the Th2 Locus Control Region

The T helper type 2 (Th2) locus control region (LCR) regulates Th2 cell differentiation. Several transcription factors bind to the LCR to modulate the expression of Th2 cytokine genes, but the molecular mechanisms behind Th2 cytokine gene regulation are incompletely understood. Here, we used databas...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kim, Kiwan, Kim, Najung, Lee, Gap Ryol
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740509/
https://ncbi.nlm.nih.gov/pubmed/26840450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148576
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