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Transcription Factors Oct-1 and GATA-3 Cooperatively Regulate Th2 Cytokine Gene Expression via the RHS5 within the Th2 Locus Control Region

The T helper type 2 (Th2) locus control region (LCR) regulates Th2 cell differentiation. Several transcription factors bind to the LCR to modulate the expression of Th2 cytokine genes, but the molecular mechanisms behind Th2 cytokine gene regulation are incompletely understood. Here, we used databas...

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Pubblicato in:PLoS One
Autori principali: Kim, Kiwan, Kim, Najung, Lee, Gap Ryol
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740509/
https://ncbi.nlm.nih.gov/pubmed/26840450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148576
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