Hypersensitive site 6 of the Th2 locus control region is essential for Th2 cytokine expression

The T helper type 2 (Th2) cytokine genes Il4, Il5, and Il13 are contained within a 140-kb region of mouse chromosome 11 and their expression is controlled by a locus control region (LCR) embedded within this locus. The LCR is composed of a number of DNase I–hypersensitive sites (HSs), which are beli...

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Detaylı Bibliyografya
Asıl Yazarlar: Williams, Adam, Lee, Gap Ryol, Spilianakis, Charalampos G., Hwang, Soo Seok, Eisenbarth, Stephanie C., Flavell, Richard A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2013
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637752/
https://ncbi.nlm.nih.gov/pubmed/23569250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304720110
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