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Demethylation of a specific hypersensitive site in the Th2 locus control region
A growing body of literature has examined and implicated DNA methylation as a critical epigenetic modification in T helper (Th) cell differentiation. The absence of DNA methyltransferases or methyl-binding proteins derepresses many cytokine loci, allowing their ectopic expression, while methylation...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2040439/ https://ncbi.nlm.nih.gov/pubmed/17940027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708293104 |
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