Competitive Mirror Image Phage Display Derived Peptide Modulates Amyloid Beta Aggregation and Toxicity

Alzheimer´s disease is the most prominent type of dementia and currently no causative treatment is available. According to recent studies, oligomeric species of the amyloid beta (Aβ) peptide appear to be the most toxic Aβ assemblies. Aβ monomers, however, may be not toxic per se and may even have a...

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Vydáno v:PLoS One
Hlavní autoři: Rudolph, Stephan, Klein, Antonia Nicole, Tusche, Markus, Schlosser, Christine, Elfgen, Anne, Brener, Oleksandr, Teunissen, Charlotte, Gremer, Lothar, Funke, Susanne Aileen, Kutzsche, Janine, Willbold, Dieter
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740492/
https://ncbi.nlm.nih.gov/pubmed/26840229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147470
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