Targeting IL-17A in Multiple Myeloma: A Potential Novel Therapeutic Approach in Myeloma

We have previously demonstrated that interleukin-17A (IL-17) producing Th17 cells are significantly elevated in blood and bone marrow (BM) in multiple myeloma (MM) and IL-17A promotes MM cell growth via the expression of IL-17 receptor. In this study, we evaluated anti-human IL-17A human monoclonal...

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Publié dans:Leukemia
Auteurs principaux: Prabhala, Rao H., Fulciniti, Mariateresa, Pelluru, Dheeraj, Rashid, Naim, Nigroiu, Andreea, Nanjappa, Puru, Pai, Christine, Lee, Saem, Prabhala, Nithya S., Bandi, Rajya Lakshmi, Smith, Robert, Lazo-Kallanian, Suzan B., Valet, Sonia, Raje, Noopur, Gold, Jason S., Richardson, Paul G., Daley, John F., Anderson, Kenneth C., Ettenberg, Seth A., Di Padova, Franco, Munshi, Nikhil C.
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740263/
https://ncbi.nlm.nih.gov/pubmed/26293646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2015.228
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