Loading...

A vocabulary of ancient peptides at the origin of folded proteins

The seemingly limitless diversity of proteins in nature arose from only a few thousand domain prototypes, but the origin of these themselves has remained unclear. We are pursuing the hypothesis that they arose by fusion and accretion from an ancestral set of peptides active as co-factors in RNA-depe...

Full description

Saved in:
Bibliographic Details
Published in:eLife
Main Authors: Alva, Vikram, Söding, Johannes, Lupas, Andrei N
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739770/
https://ncbi.nlm.nih.gov/pubmed/26653858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09410
Tags: Add Tag
No Tags, Be the first to tag this record!