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A vocabulary of ancient peptides at the origin of folded proteins

The seemingly limitless diversity of proteins in nature arose from only a few thousand domain prototypes, but the origin of these themselves has remained unclear. We are pursuing the hypothesis that they arose by fusion and accretion from an ancestral set of peptides active as co-factors in RNA-depe...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Alva, Vikram, Söding, Johannes, Lupas, Andrei N
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739770/
https://ncbi.nlm.nih.gov/pubmed/26653858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09410
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