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A vocabulary of ancient peptides at the origin of folded proteins

The seemingly limitless diversity of proteins in nature arose from only a few thousand domain prototypes, but the origin of these themselves has remained unclear. We are pursuing the hypothesis that they arose by fusion and accretion from an ancestral set of peptides active as co-factors in RNA-depe...

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書目詳細資料
發表在:eLife
Main Authors: Alva, Vikram, Söding, Johannes, Lupas, Andrei N
格式: Artigo
語言:Inglês
出版: eLife Sciences Publications, Ltd 2015
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739770/
https://ncbi.nlm.nih.gov/pubmed/26653858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09410
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