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Complex interactions between the DNA-damage response and mammalian telomeres
Natural chromosome ends resemble double-stranded DNA breaks, but they do not activate a damage response in healthy cells. Telomeres therefore have evolved to solve the ‘end-protection problem’ by inhibiting multiple DNA damage–response pathways. During the past decade, the view of telomeres has prog...
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| Publicado en: | Nat Struct Mol Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4739752/ https://ncbi.nlm.nih.gov/pubmed/26581520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3092 |
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