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Mammalian 5’ C-rich telomeric overhangs are a mark of recombination-dependent telomere maintenance

Recent evidence for 5’ cytosine (C)-rich overhangs at the telomeres of the nematode C. elegans provided the impetus to re-examine the end structure of mammalian telomeres. Two-dimensional (2D) gel electrophoresis, Single Telomere Length Analysis (STELA) and strand-specific exonuclease assays reveale...

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Détails bibliographiques
Auteurs principaux: Oganesian, Liana, Karlseder, Jan
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082866/
https://ncbi.nlm.nih.gov/pubmed/21504833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.03.015
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