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5′ C-rich telomeric overhangs are an outcome of rapid telomere truncation events
A subset of human tumors ensures indefinite telomere length maintenance by activating a telomerase-independent mechanism known as Alternative Lengthening of Telomeres (ALT). Most tumor cells of ALT origin share a constellation of unique characteristics, which include large stores of extra-chromosoma...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3594334/ https://ncbi.nlm.nih.gov/pubmed/23347616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2012.12.008 |
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