Flavonoid Compound Icariin Activates Hypoxia Inducible Factor-1α in Chondrocytes and Promotes Articular Cartilage Repair

Articular cartilage has poor capability for repair following trauma or degenerative pathology due to avascular property, low cell density and migratory ability. Discovery of novel therapeutic approaches for articular cartilage repair remains a significant clinical need. Hypoxia is a hallmark for car...

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Publicat a:PLoS One
Autors principals: Wang, Pengzhen, Zhang, Fengjie, He, Qiling, Wang, Jianqi, Shiu, Hoi Ting, Shu, Yinglan, Tsang, Wing Pui, Liang, Shuang, Zhao, Kai, Wan, Chao
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739592/
https://ncbi.nlm.nih.gov/pubmed/26841115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148372
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