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Hypoxia. HIF-mediated articular chondrocyte function: prospects for cartilage repair

In a chronically hypoxic tissue such as cartilage, adaptations to hypoxia do not merely include cell survival responses, but also promotion of its specific function. This review will focus on describing such hypoxia-mediated chondrocyte function, in particular in the permanent articular cartilage. T...

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Bibliographic Details
Main Authors: Murphy, Christopher L, Thoms, Brendan L, Vaghjiani, Rasilaben J, Lafont, Jérôme E
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688225/
https://ncbi.nlm.nih.gov/pubmed/19232075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2574
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