Flavonoid Compound Icariin Activates Hypoxia Inducible Factor-1α in Chondrocytes and Promotes Articular Cartilage Repair

Articular cartilage has poor capability for repair following trauma or degenerative pathology due to avascular property, low cell density and migratory ability. Discovery of novel therapeutic approaches for articular cartilage repair remains a significant clinical need. Hypoxia is a hallmark for car...

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Publicado no:PLoS One
Main Authors: Wang, Pengzhen, Zhang, Fengjie, He, Qiling, Wang, Jianqi, Shiu, Hoi Ting, Shu, Yinglan, Tsang, Wing Pui, Liang, Shuang, Zhao, Kai, Wan, Chao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739592/
https://ncbi.nlm.nih.gov/pubmed/26841115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148372
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