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Taking a Measured Approach to Toxicity Data in Phase I Oncology Clinical Trials
The standard categorical system for assessing attribution of toxicity to study drug(s) in phase I trials is cumbersome and uninformative. While a binary system (‘related’ versus ‘unrelated’) would be sufficient to define maximum tolerated dose, a probability estimation would better support dose sele...
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| Publicado no: | Clin Cancer Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4738103/ https://ncbi.nlm.nih.gov/pubmed/26467385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2005 |
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