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Analysis of Impact of Post-Treatment Biopsies in Phase I Clinical Trials

PURPOSE: The use of biopsy-derived pharmacodynamic biomarkers is increasing in early-phase clinical trials. It remains unknown whether drug development is accelerated or enhanced by their use. We examined the impact of biopsy-derived pharmacodynamic biomarkers on subsequent drug development through...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Sweis, Randy F., Drazer, Michael W., Ratain, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872035/
https://ncbi.nlm.nih.gov/pubmed/26668350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2015.63.6126
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