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Persistent Electrical Activity in Primary Nociceptors after Spinal Cord Injury Is Maintained by Scaffolded Adenylyl Cyclase and Protein Kinase A and Is Associated with Altered Adenylyl Cyclase Regulation

Little is known about intracellular signaling mechanisms that persistently excite neurons in pain pathways. Persistent spontaneous activity (SA) generated in the cell bodies of primary nociceptors within dorsal root ganglia (DRG) has been found to make major contributions to chronic pain in a rat mo...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Bavencoffe, Alexis, Li, Yong, Wu, Zizhen, Yang, Qing, Herrera, Juan, Kennedy, Eileen J., Walters, Edgar T., Dessauer, Carmen W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737775/
https://ncbi.nlm.nih.gov/pubmed/26843647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0895-15.2016
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