Scaffolding by A-Kinase Anchoring Protein Enhances Functional Coupling between Adenylyl Cyclase and TRPV1 Channel

Scaffolding proteins often bring kinases together with their substrates to facilitate cell signaling. This arrangement is critical for the phosphorylation and regulation of the transient receptor potential vanilloid 1 (TRPV1) channel, a key target of inflammatory mediators such as prostaglandins. Th...

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Bibliografische gegevens
Hoofdauteurs: Efendiev, Riad, Bavencoffe, Alexis, Hu, Hongzhen, Zhu, Michael X., Dessauer, Carmen W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2013
Onderwerpen:
Signal Transduction
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567646/
https://ncbi.nlm.nih.gov/pubmed/23264624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.428144
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