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Scaffolding by A-Kinase Anchoring Protein Enhances Functional Coupling between Adenylyl Cyclase and TRPV1 Channel

Scaffolding proteins often bring kinases together with their substrates to facilitate cell signaling. This arrangement is critical for the phosphorylation and regulation of the transient receptor potential vanilloid 1 (TRPV1) channel, a key target of inflammatory mediators such as prostaglandins. Th...

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Autors principals: Efendiev, Riad, Bavencoffe, Alexis, Hu, Hongzhen, Zhu, Michael X., Dessauer, Carmen W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567646/
https://ncbi.nlm.nih.gov/pubmed/23264624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.428144
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