EPAC1 and EPAC2 promote nociceptor hyperactivity associated with chronic pain after spinal cord injury

Chronic pain following spinal cord injury (SCI) is associated with electrical hyperactivity (spontaneous and evoked) in primary nociceptors. Cyclic adenosine monophosphate (cAMP) signaling is an important contributor to nociceptor excitability, and knockdown of the cAMP effector, exchange protein ac...

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Dettagli Bibliografici
Pubblicato in:Neurobiol Pain
Autori principali: Berkey, Samantha C., Herrera, Juan J., Odem, Max A., Rahman, Simran, Cheruvu, Sai S., Cheng, Xiaodong, Walters, Edgar T., Dessauer, Carmen W., Bavencoffe, Alexis G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
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Original Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926371/
https://ncbi.nlm.nih.gov/pubmed/31890991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ynpai.2019.100040
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