EPAC1 and EPAC2 promote nociceptor hyperactivity associated with chronic pain after spinal cord injury

Chronic pain following spinal cord injury (SCI) is associated with electrical hyperactivity (spontaneous and evoked) in primary nociceptors. Cyclic adenosine monophosphate (cAMP) signaling is an important contributor to nociceptor excitability, and knockdown of the cAMP effector, exchange protein ac...

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Detalhes bibliográficos
Publicado no:Neurobiol Pain
Main Authors: Berkey, Samantha C., Herrera, Juan J., Odem, Max A., Rahman, Simran, Cheruvu, Sai S., Cheng, Xiaodong, Walters, Edgar T., Dessauer, Carmen W., Bavencoffe, Alexis G.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926371/
https://ncbi.nlm.nih.gov/pubmed/31890991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ynpai.2019.100040
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