Determination of the binding mode for anti-inflammatory natural product xanthohumol with myeloid differentiation protein 2

It is recognized that myeloid differentiation protein 2 (MD-2), a coreceptor of toll-like receptor 4 (TLR4) for innate immunity, plays an essential role in activation of the lipopolysaccharide signaling pathway. MD-2 is known as a neoteric and suitable therapeutical target. Therefore, there is great...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Fu, Weitao, Chen, Lingfeng, Wang, Zhe, Zhao, Chengwei, Chen, Gaozhi, Liu, Xing, Dai, Yuanrong, Cai, Yuepiao, Li, Chenglong, Zhou, Jianmin, Liang, Guang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737557/
https://ncbi.nlm.nih.gov/pubmed/26869767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S98466
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