Discovery and evaluation of novel anti-inflammatory derivatives of natural bioactive curcumin

Curcumin is a natural active product that has various pharmacological activities such as anti-inflammatory effects. Here, we report the synthesis and evaluation of 34 monocarbonyl curcumin analogs as novel anti-inflammatory agents. Among the analogs, the symmetrical heterocyclic type displayed the s...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Zhang, Yali, Jiang, Xin, Peng, Kesong, Chen, Chengwei, Fu, Lili, Wang, Zhe, Feng, Jianpeng, Liu, Zhiguo, Zhang, Huajie, Liang, Guang, Pan, Zheer
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2014
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226458/
https://ncbi.nlm.nih.gov/pubmed/25395833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S69914
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