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ASSESSMENT OF SUBUNIT-DEPENDENT DIRECT GATING AND ALLOSTERIC MODULATORY EFFECTS OF CARISOPRODOL AT GABA(A) RECEPTORS
Carisoprodol is a widely prescribed muscle relaxant, abuse of which has grown considerably in recent years. It directly activates and allosterically modulates α1β2γ2 GABA(A)Rs, although the site(s) of action are unknown. To gain insight into the actions of carisoprodol, subunit-dependent effects of...
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| Опубликовано в: : | Neuropharmacology |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4737552/ https://ncbi.nlm.nih.gov/pubmed/25896767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.04.007 |
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