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Carisoprodol-Mediated Modulation of GABA(A) Receptors: In Vitro and in Vivo Studies

Carisoprodol is a frequently prescribed muscle relaxant. In recent years, this drug has been increasingly abused. The effects of carisoprodol have been attributed to its metabolite, meprobamate, a controlled substance that produces sedation via GABA(A) receptors (GABA(A)Rs). Given the structural sim...

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Main Authors: Gonzalez, Lorie A., Gatch, Michael B., Taylor, Cynthia M., Bell-Horner, Cathy L., Forster, Michael J., Dillon, Glenn H.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Pharmacology and Experimental Therapeutics 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672873/
https://ncbi.nlm.nih.gov/pubmed/19244096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.151142
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