KIR2DL3 and KIR2DL1 show similar impact on licensing of human NK cells

Killer cell immunoglobulin‐like receptor/HLA class I (KIR/HLA‐I) combinations are associated with disease risk, implicating functional roles for NK cells (NKCs) or KIR(+) T cells. KIR/HLA‐I interactions can act through inhibition of NKC activation by target cells and NKC licensing for greater intrin...

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Udgivet i:Eur J Immunol
Main Authors: Sim, Malcolm J. W., Stowell, Janet, Sergeant, Ruhena, Altmann, Daniel M., Long, Eric O., Boyton, Rosemary J.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2015
Fag:
Innate immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737201/
https://ncbi.nlm.nih.gov/pubmed/26467237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545757
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