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TNF-α mediates choroidal neovascularization by upregulating VEGF expression in RPE through ROS-dependent β-catenin activation

PURPOSE: Inflammation, oxidative stress, and angiogenesis have been proposed to interact in age-related macular degeneration. It has been postulated that external stimuli that cause oxidative stress can increase production of vascular endothelial growth factor (VEGF) in retinal pigment epithelial (R...

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Detalhes bibliográficos
Publicado no:Mol Vis
Main Authors: Wang, Haibo, Han, Xiaokun, Wittchen, Erika S., Hartnett, M. Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736754/
https://ncbi.nlm.nih.gov/pubmed/26900328
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