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Upregulation of CCR3 by Age-Related Stresses Promotes Choroidal Endothelial Cell Migration via VEGF-Dependent and -Independent Signaling

PURPOSE. To explore the molecular mechanisms by which the C–C chemokine receptor type 3 (CCR3) and chemokine (C–C motif) ligand 11 (CCL11) regulate choroidal endothelial cell (CEC) migration and the interactions with the vascular endothelial growth factor (VEGF) signaling pathway. METHODS. Human ret...

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Detalhes bibliográficos
Main Authors: Wang, Haibo, Wittchen, Erika S., Jiang, Yanchao, Ambati, Balamurali, Grossniklaus, Hans E., Hartnett, M. Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208059/
https://ncbi.nlm.nih.gov/pubmed/21917937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8230
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