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Heterotypic RPE-choroidal endothelial cell contact increases choroidal endothelial cell transmigration via PI 3-kinase and Rac1

Age-related macular degeneration (AMD) is the major cause of non-preventable blindness. Severe forms of AMD involve breaching of the retinal pigment epithelial (RPE) barrier by underlying choroidal endothelial cells (CECs), followed by migration into, and subsequent neovascularization of the neurose...

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Détails bibliographiques
Auteurs principaux: Peterson, Lynda J., Wittchen, Erika S., Geisen, Pete, Burridge, Keith, Hartnett, M. Elizabeth
Format: Artigo
Langue:Inglês
Publié: 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270476/
https://ncbi.nlm.nih.gov/pubmed/17292356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2006.12.012
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