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Altered cellular localization and hemichannel activities of KID syndrome associated connexin26 I30N and D50Y mutations
BACKGROUND: Gap junctions facilitate exchange of small molecules between adjacent cells, serving a crucial function for the maintenance of cellular homeostasis. Mutations in connexins, the basic unit of gap junctions, are associated with several human hereditary disorders. For example, mutations in...
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| 發表在: | BMC Cell Biol |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4736630/ https://ncbi.nlm.nih.gov/pubmed/26831144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-016-0081-0 |
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