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Altered CO (2) sensitivity of connexin26 mutant hemichannels in vitro

Connexin26 (Cx26) mutations underlie human pathologies ranging from hearing loss to keratitis ichthyosis deafness (KID) syndrome. Cx26 hemichannels are directly gated by CO (2) and contribute to the chemosensory regulation of breathing. The KID syndrome mutation A88V is insensitive to CO (2), and ha...

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Dades bibliogràfiques
Publicat a:Physiol Rep
Autors principals: de Wolf, Elizabeth, van de Wiel, Joseph, Cook, Jonathan, Dale, Nicholas
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357999/
https://ncbi.nlm.nih.gov/pubmed/27884957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13038
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