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Altered CO (2) sensitivity of connexin26 mutant hemichannels in vitro
Connexin26 (Cx26) mutations underlie human pathologies ranging from hearing loss to keratitis ichthyosis deafness (KID) syndrome. Cx26 hemichannels are directly gated by CO (2) and contribute to the chemosensory regulation of breathing. The KID syndrome mutation A88V is insensitive to CO (2), and ha...
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| Gepubliceerd in: | Physiol Rep |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
John Wiley and Sons Inc.
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5357999/ https://ncbi.nlm.nih.gov/pubmed/27884957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13038 |
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