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Altered cellular localization and hemichannel activities of KID syndrome associated connexin26 I30N and D50Y mutations

BACKGROUND: Gap junctions facilitate exchange of small molecules between adjacent cells, serving a crucial function for the maintenance of cellular homeostasis. Mutations in connexins, the basic unit of gap junctions, are associated with several human hereditary disorders. For example, mutations in...

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Detalhes bibliográficos
Publicado no:BMC Cell Biol
Main Authors: Aypek, Hande, Bay, Veysel, Meşe, Gülistan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736630/
https://ncbi.nlm.nih.gov/pubmed/26831144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-016-0081-0
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