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The dual specificity phosphatase 2 gene is hypermethylated in human cancer and regulated by epigenetic mechanisms
BACKGROUND: Dual specificity phosphatases are a class of tumor-associated proteins involved in the negative regulation of the MAP kinase pathway. Downregulation of the dual specificity phosphatase 2 (DUSP2) has been reported in cancer. Epigenetic silencing of tumor suppressor genes by abnormal promo...
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| 出版年: | BMC Cancer |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4736155/ https://ncbi.nlm.nih.gov/pubmed/26833217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2087-6 |
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