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Detecting O(2) binding sites in protein cavities

Internal cavities are important elements in protein structure, dynamics, stability and function. Here we use NMR spectroscopy to investigate the binding of molecular oxygen (O(2)) to cavities in a well-studied model for ligand binding, the L99A mutant of T4 lysozyme. On increasing the O(2) concentra...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Kitahara, Ryo, Yoshimura, Yuichi, Xue, Mengjun, Kameda, Tomoshi, Mulder, Frans A. A.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735865/
https://ncbi.nlm.nih.gov/pubmed/26830762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20534
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