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Detecting O(2) binding sites in protein cavities

Internal cavities are important elements in protein structure, dynamics, stability and function. Here we use NMR spectroscopy to investigate the binding of molecular oxygen (O(2)) to cavities in a well-studied model for ligand binding, the L99A mutant of T4 lysozyme. On increasing the O(2) concentra...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kitahara, Ryo, Yoshimura, Yuichi, Xue, Mengjun, Kameda, Tomoshi, Mulder, Frans A. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735865/
https://ncbi.nlm.nih.gov/pubmed/26830762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20534
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