Graded Proteasome Dysfunction in Caenorhabditis elegans Activates an Adaptive Response Involving the Conserved SKN-1 and ELT-2 Transcription Factors and the Autophagy-Lysosome Pathway

The maintenance of cellular proteins in a biologically active and structurally stable state is a vital endeavor involving multiple cellular pathways. One such pathway is the ubiquitin-proteasome system that represents a major route for protein degradation, and reductions in this pathway usually have...

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Detaylı Bibliyografya
Yayımlandı:PLoS Genet
Asıl Yazarlar: Keith, Scott A., Maddux, Sarah K., Zhong, Yayu, Chinchankar, Meghna N., Ferguson, Annabel A., Ghazi, Arjumand, Fisher, Alfred L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734690/
https://ncbi.nlm.nih.gov/pubmed/26828939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005823
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