Dimerization of the SP1 Region of HIV-1 Gag Induces a Helical Conformation and Association into Helical Bundles: Implications for Particle Assembly

HIV-1 immature particle (virus-like particle [VLP]) assembly is mediated largely by interactions between the capsid (CA) domains of Gag molecules but is facilitated by binding of the nucleocapsid (NC) domain to nucleic acid. We previously investigated the role of SP1, a “spacer” between CA and NC, i...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Datta, Siddhartha A. K., Clark, Patrick K., Fan, Lixin, Ma, Buyong, Harvin, Demetria P., Sowder, Raymond C., Nussinov, Ruth, Wang, Yun-Xing, Rein, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733982/
https://ncbi.nlm.nih.gov/pubmed/26637452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02061-15
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados