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On the Role of the SP1 Domain in HIV-1 Particle Assembly: a Molecular Switch?
Expression of a retroviral protein, Gag, in mammalian cells is sufficient for assembly of immature virus-like particles (VLPs). VLP assembly is mediated largely by interactions between the capsid (CA) domains of Gag molecules but is facilitated by binding of the nucleocapsid (NC) domain to nucleic a...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3126284/ https://ncbi.nlm.nih.gov/pubmed/21325421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00006-11 |
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