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On the Role of the SP1 Domain in HIV-1 Particle Assembly: a Molecular Switch?
Expression of a retroviral protein, Gag, in mammalian cells is sufficient for assembly of immature virus-like particles (VLPs). VLP assembly is mediated largely by interactions between the capsid (CA) domains of Gag molecules but is facilitated by binding of the nucleocapsid (NC) domain to nucleic a...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3126284/ https://ncbi.nlm.nih.gov/pubmed/21325421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00006-11 |
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