On the Role of the SP1 Domain in HIV-1 Particle Assembly: a Molecular Switch?

Expression of a retroviral protein, Gag, in mammalian cells is sufficient for assembly of immature virus-like particles (VLPs). VLP assembly is mediated largely by interactions between the capsid (CA) domains of Gag molecules but is facilitated by binding of the nucleocapsid (NC) domain to nucleic a...

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Bibliografiska uppgifter
Huvudupphovsmän: Datta, Siddhartha A. K., Temeselew, Lakew G., Crist, Rachael M., Soheilian, Ferri, Kamata, Anne, Mirro, Jane, Harvin, Demetria, Nagashima, Kunio, Cachau, Raul E., Rein, Alan
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2011
Ämnen:
Structure and Assembly
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126284/
https://ncbi.nlm.nih.gov/pubmed/21325421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00006-11
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