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Functional Redundancy in HIV-1 Viral Particle Assembly
Expression of a retroviral Gag protein in mammalian cells leads to the assembly of virus particles. In vitro, recombinant Gag proteins are soluble but assemble into virus-like particles (VLPs) upon addition of nucleic acid. We have proposed that Gag undergoes a conformational change when it is at a...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3497692/ https://ncbi.nlm.nih.gov/pubmed/22993163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06287-11 |
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